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Methadone, sold under the brand name Dolophine among others, is an opioid used to treat pain and as maintenance therapy or to help with tapering in people with opioid dependence.
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Methadone is indicated for the maintenance treatment of opioid dependence (i.e. opioid use disorder per the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM). A 2009 Cochrane review found that it was effective in retaining people in treatment and in the reduction or cessation of heroin use as measured by self-report and urine/hair analysis but did not affect criminal activity or risk of death. Want Pain Relief medication? You can Buy it online –Buy methadone 10mg online here.
The treatment of opioid-dependent persons with it will follow one of two routes. it maintenance therapy (MMT) is prescribed to individuals who wish to abstain from illicit drug use but have failed to maintain abstinence from opioids for significant periods. The duration of its maintenance ranges from a few months to lifelong. It reduction programs are suitable for addicted persons who wish to completely stop using drugs.
The length of the reduction program will depend on the starting dose and speed of reduction, this varies between clinics and from person to person. In addition, enrollment in methadone maintenance has the potential to reduce the transmission of infectious diseases associated with opiate injection, such as hepatitis and HIV. Want Pain Relief medication? The principal goals of its maintenance are to relieve opioid cravings, suppress the abstinence syndrome, and block the euphoric effects associated with opioids.
However, it abuse does carry the potential for dependence. When used correctly, methadone maintenance has been found to be medically safe and non-sedating and provides a slow recovery from opioid addiction. It is also indicated for pregnant women addicted to opioids. Want Pain Relief medication?
Adverse effects of methadone:
- Diarrhea or constipation
- Perspiration and sweating
- Heat intolerance
- Dizziness or fainting
- Chronic fatigue, sleepiness, and exhaustion
- Sleep problems such as drowsiness, trouble falling
- asleep (Insomnia), and trouble staying asleep
- Constricted pupils
- Dry mouth
- Nausea and vomiting
- Low blood pressure
- Difficulty urinating
- Mood changes, euphoria, disorientation
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